Epigenetics & Nuclear Signaling Recombinant Proteins

Human LSM4 Recombinant Protein (RPES1824)

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RPES1824

Description

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Human LSM4 Recombinant Protein

U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif and are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. LSM4 forms a heteromer with a donut shape. The complexes are involved in various steps of RNA metabolism. LSM4 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM4 contributes RNA protein interactions and structural changes which are essential during ribosomal subunit assembly.

Product Name:Human LSM4 Recombinant Protein (RPES1824)
Product Code:RPES1824
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:U6 snRNA-Associated Sm-Like Protein LSm4, Glycine-Rich Protein, GRP, LSM4
Accession:Q9Y4Z0
Sequence:Met 1-Gln139
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm4 is produced by our E.coli expression system and the target gene encoding Met1-Gln139 is expressed with a 6His tag at the N-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:17.5 kDa
AP Mol Mass:17 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.0 .
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Epigenetics & Nuclear Signaling
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