Immunology Recombinant Proteins

Human LMIR2/CD300C Recombinant Protein (RPES3505)

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SKU:
RPES3505
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

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Human LMIR2/CD300C Recombinant Protein

CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells; granulocytes; most myeloid cells; dendritic cells; and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.

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