Human LILRB4/CD85k/ILT3 Recombinant Protein (RPES0715)

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SKU:
RPES0715
Product Type:
Recombinant Protein
Species:
Human

Description

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Human LILRB4/CD85k/ILT3 Recombinant Protein

The leukocyte immunoglobulin-like receptor (LILR) B4 belongs to a family of cell surface receptors that possesses cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases.The LILRB4 is a central inhibitory receptor in uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface.

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