The immunoglobulin-like transcript (ILT) family (also named leukocyte Ig-like receptors (LIR) and monocyte/macrophage Ig-like receptors (MIR)) can be activating and inhibitory immunoreceptors. ILTs are expressed on many leukocyte subsets and regulators of immune responses . ILTs share significant homology with killer cell Ig-like receptors (KIR). Except ILT-6, all ILT family members are type I transmembrane proteins having two or four extracellular Ig-like domains . ILT2 is expressed on most monocytes,dendritic cells,and mature B cells. ILT2 is also expressed on small percentages of T-cells and NK cells. ILT2 can prevents cellular activation.
Product Name:
Human LILRB1 Recombinant Protein (RPES1264)
Product Code:
RPES1264
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1, LIR-1, Leukocyte Immunoglobulin-Like Receptor 1, CD85 Antigen-Like Family Member J, Immunoglobulin-Like Transcript 2, ILT-2, Monocyte/Macrophage Immunoglobulin-Like Receptor 7, MIR-7, CD85j, LILRB1, ILT2, LIR1, MIR7
Accession:
ADJ55949.1
Sequence:
Gly24-His458
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 is produced by our Mammalian expression system and the target gene encoding Gly24-His458 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
48.2 kDa
AP Mol Mass:
79 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
