Immune Checkpoint Recombinant Proteins
Human LIGHT Recombinant Protein (hFc Tag) (HDPT0161)
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- SKU:
- HDPT0161
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human LIGHT Recombinant Protein (hFc Tag)
| Description: | The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. |
| Product name: | Human LIGHT Recombinant Protein (hFc Tag) |
| Synonyms: | TNFSF14, CD258， HVEML， LIGHT， LTg |
| Type: | protein |
| Size: | 50 µg |
| Name: | LIGHT |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | N-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | hFc（Glu99-Ala330）+LIGHT（Leu83-Val240） |
| Gene ID: | 8740 |
| Uniprot: | O43557 |
| Molecular Weight: | 43.4 kDa |
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