Human LGR5 Full-Length Bioactive Membrane Protein (HDFP054)

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SKU:
HDFP054
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
O75473

Description

system_update_altDatasheet
Product nameHuman LGR5 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP054
Product CategoryFull Length Transmembrane Proteins
Target:LGR5
Uniprot:O75473
Description:Human LGR5 full length protein-synthetic nanodisc
Molecular Weight:The human full length LGR5 protein has a MW of 100.0 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:FEX; GPR49; GPR67; GRP49; HG38
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:The protein is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Delivery:In Stock
UsageResearch use only
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