Human LGR4 Full-Length Bioactive Membrane Protein (HDFP053)

(No reviews yet) Write a Review
SKU:
HDFP053
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q9BXB1

Description

system_update_altDatasheet
Product nameHuman LGR4 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP053
Product CategoryFull Length Transmembrane Proteins
Target:LGR4
Uniprot:Q9BXB1
Description:Human LGR4 full length protein-synthetic nanodisc
Molecular Weight:The human full length LGR4 protein has a MW of 104.5 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:BNMD17; GPR48
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye.
Delivery:In Stock
UsageResearch use only
View AllClose

0 Reviews

View AllClose

Related Products