Human LFA-3/CD58 Recombinant Protein (RPES1028)
- SKU:
- RPES1028
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human LFA-3/CD58 Recombinant Protein
Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes; erythrocytes; endothelial cells; epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells; antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition; the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
| Product Name: | Human LFA-3/CD58 Recombinant Protein (RPES1028) |
| Product Code: | RPES1028 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Lymphocyte Function-Associated Antigen 3, Surface Glycoprotein LFA-3, CD58, LFA3?Ag3, CD58 antigen |
| Accession: | P19256 |
| Sequence: | Phe29-Arg215(His147Tyr? |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215(His147Tyr? is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 22.5 kDa |
| AP Mol Mass: | 30-60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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