PTGDS, also known as L-PGDS, belongs to the calycin superfamily?lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of PGH2 to PGD2. It is involved in smooth muscle contraction/relaxation and a variety of central nervous system functions. PTGDS may have an anti-apoptotic role in oligodendrocytes. It binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
Product Name:
Human LECT1 Recombinant Protein (RPES0172)
Product Code:
RPES0172
Size:
20µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
BRICD3,CHM-I,CHM1,MYETS1
Accession:
NP_001011705.1
Sequence:
Glu215-Val333
Fusion tag:
N-Fc
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human LECT1 (NP_001011705.1) (Glu215-Val333) was expressed with the Fc region of human IgG1 at the N-terminus.
Purity:
> (81.7+13.6) % as determined by reducing SDS-PAGE..
Mol Mass:
42.1 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
