Human LAMB1 / Laminin subunit beta-1 ELISA Kit

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SKU:
HUFI02043
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P07942
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
LAMB1, CLM, Laminin-6 subunit beta, Laminin-2 subunit beta, Laminin-12 subunit beta, Laminin-10 subunit beta, Laminin-8 subunit beta, Laminin B1 chain, Laminin-1 subunit beta
Reactivity:
Human
Research Area:
Cell Biology

Description

Human LAMB1 / Laminin subunit beta-1 ELISA

LAMB1 (Laminin Subunit Beta 1) encodes a subunit of laminin, a proteoglycan that is found primarily in the extracellular matrix of basal epithelia, where it functions as a major ligand for integrins on the surface of neighboring cells. LAMB1 forms a sheet-like network through homophilic binding between extracellular domain interactions. Mutations at this locus have been associated with autosomal dominant Opitz Syndrome, which can be characterized by midline facial defects, severe mental retardation, postaxial polydactyly and a predisposition for congenital heart disease.

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