Immune Checkpoint Recombinant Proteins
Human KLRC1 Recombinant Protein (hFc Tag) (HDPT0251)
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- SKU:
- HDPT0251
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human KLRC1 Recombinant Protein (hFc Tag)
| Description: | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Product name: | Human KLRC1 Recombinant Protein (hFc Tag) |
| Synonyms: | CD159A; NKG2; NKG2A |
| Type: | protein |
| Size: | 50 µg |
| Name: | KLRC1 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | Contact Technical Support |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | N-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | hFc(Glu99-Ala330)+KLRC1(Pro94-Leu233) |
| Gene ID: | |
| Uniprot: | P26715 |
| Molecular Weight: | 40.92 kDa |
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