Human KLF4 Recombinant Protein (RPPB3795)

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SKU:
RPPB3795
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
O43474

Description

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Product Name:Human KLF4 Recombinant Protein
Product Code:RPPB3795
Size:20µg
Species:Human
Target:KLF4
Synonyms:Kruppel-LikeFactor 4 (Gut), GKLF, EZF, Epithelial Zinc Finger Protein EZF, Gut-EnrichedKrueppel-Like Factor, Endothelial Kruppel-Like Zinc Finger Protein,Krueppel-Like Factor 4, Krueppel-like factor 4, Epithelial zinc finger proteinEZF, Gut-enriched krueppel-like factor.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:KLF4 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence:MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMAVS DALLPSFSTF ASGPAGREKT LRQAGAPNNR WREELSHMKRLPPVLPGRPY DLAAATVATD LESGGAGAAC GGSNLAPLPR RETEEFNDLL DLDFILSNSL THPPESVAATVSSSASASSS SSPSSSGPAS APSTCSFTYP IRAGNDPGVA PGGTGGGLLY GRESAPPPTA PFNLADINDVSPSGGFVAEL LRPELDPVYI PPQQPQPPGG GLMGKFVLKA SLSAPGSEYG SPSVISVSKG SPDGSHPVVVAPYNGGPPRT CPKIKQEAVS SCTHLGAGPP LSNGHRPAAH DFPLGRQLPS RTTPTLGLEE VLSSRDCHPALPLPPGFHPH PGPNYPSFLP DQMQPQVPPL HYQELMPPGS CMPEEPKPKR GRRSWPRKRT AT

KLF4 is a transcription factor that performs as both an activator and repressor. KLF4 is expressed mainly in erythroid tissues and found mostly in gut. KLF4 is takes part in the differentiation of epithelial cells in addition to skeletal and kidney development.

KLF4 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 422 amino acids (11-395 a.a) andhaving a molecular mass of 44.2kDa.KLF4 is fused to a 37 aminoacid His-tag at N-terminus & purified by proprietary chromatographictechniques.

UniProt Code:O43474
NCBI GenInfo Identifier:194248077
NCBI Gene ID:9314
NCBI Accession:NP_004226.3
UniProt Secondary Accession:O43474,P78338, Q5T3J8, Q5T3J9, Q8N717, Q9UNP3, B2R8S4 B3KT79, L0R3I6, L0R4N5,
UniProt Related Accession:O43474
Molecular Weight:51kDa
NCBI Full Name:Krueppel-like factor 4
NCBI Synonym Full Names:Kruppel-like factor 4 (gut)
NCBI Official Symbol:KLF4��
NCBI Official Synonym Symbols:EZF; GKLF��
NCBI Protein Information:Krueppel-like factor 4; gut-enriched krueppel-like factor; epithelial zinc finger protein EZF; endothelial Kruppel-like zinc finger protein
UniProt Protein Name:Krueppel-like factor 4
UniProt Synonym Protein Names:Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor
Protein Family:Krueppel-like factor
UniProt Gene Name:KLF4��
UniProt Entry Name:KLF4_HUMAN
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