Description
Product Name: | Human KLF4 Recombinant Protein |
Product Code: | RPPB3794 |
Size: | 10µg |
Species: | Human |
Target: | KLF4 |
Synonyms: | Kruppel-like factor 4 (gut), EZF, GKLF, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, endothelial Kruppel-like zinc finger protein. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile Filtered colorless solution. |
Formulation: | The KLF4 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 10% glycerol. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 80% as determined by SDS-PAGE. |
Amino Acid Sequence: | MAHHHHHHMA DQLTEEQIAE FKEAFSLFDK DGDGTITTKE LGTVMRSLGQ NPTEAELQDM INEVDADGNG TIDFPEFLTM MARKMKDTDS EEEIREAFRV FDKDGNGYIS AAELRHVMTN LGEKLTDEEV DEMIREADID GDGQVNYEEF VQMMTAKGSM AVSDALLPSF STFASGPAGR EKTLRQAGAP NNRWREELSH MKRLPPVLPG RPYDLAAATV ATDLESGGAG AACGGSNLAP LPRRETEEFN DLLDLDFILS NSLTHPPESV AATVSSSASA SSSSSPSSSG PASAPSTCSF TYPIRAGNDP GVAPGGTGGG LLYGRESAPP PTAPFNLADI NDVSPSGGFV AELLRPELDP VYIPPQQPQP PGGGLMGKFV LKASLSAPGS EYGSPSVISV SKGSPDGSHP VVVAPYNGGP PRTCPKIKQE AVSSCTHLGA GPPLSNGHRP AAHDFPLGRQ LPSRTTPTLG LEEVLSSRDC HPALPLPPGF HPHPGPNYPS FLPDQMQPQV PPLHYQELMP PGSCMPEEPK PKRGRRSWPR KRTAT |
KLF4 is a transcription factor that performs as both an activator and repressor. KLF4 is expressed mainly in erythroid tissues and found mostly in gut. KLF4 is takes part in the differentiation of epithelial cells in addition to skeletal and kidney development.
KLF4 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 545 amino acids (11-395) and having a molecular mass of 58.1 kDa.The KLF4 is fused to a 159 amino acid His-CaM Tag at N-terminus and purified by proprietary chromatographic techniques.
UniProt Code: | O43474 |
NCBI GenInfo Identifier: | 194248077 |
NCBI Gene ID: | 9314 |
NCBI Accession: | NP_004226.3 |
UniProt Secondary Accession: | O43474,P78338, Q5T3J8, Q5T3J9, Q8N717, Q9UNP3, B2R8S4 B3KT79, L0R3I6, L0R4N5, |
UniProt Related Accession: | O43474 |
Molecular Weight: | 51kDa |
NCBI Full Name: | Krueppel-like factor 4 |
NCBI Synonym Full Names: | Kruppel-like factor 4 (gut) |
NCBI Official Symbol: | KLF4�� |
NCBI Official Synonym Symbols: | EZF; GKLF�� |
NCBI Protein Information: | Krueppel-like factor 4; gut-enriched krueppel-like factor; epithelial zinc finger protein EZF; endothelial Kruppel-like zinc finger protein |
UniProt Protein Name: | Krueppel-like factor 4 |
UniProt Synonym Protein Names: | Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor |
Protein Family: | Krueppel-like factor |
UniProt Gene Name: | KLF4�� |
UniProt Entry Name: | KLF4_HUMAN |