Human Kallikrein 11/KLK11 Recombinant Protein (RPES3575)
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- SKU:
- RPES3575
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human Kallikrein 11/KLK11 Recombinant Protein
Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide;a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.
| Product Name: | Human Kallikrein 11/KLK11 Recombinant Protein (RPES3575) |
| Product Code: | RPES3575 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP |
| Accession: | NP_006844.1 |
| Sequence: | Glu19-Asn250 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Kallikrein 11 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn250 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 26.3 kDa |
| AP Mol Mass: | 38 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; 2mM CaCl2; pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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