Human Kallikrein 1/KLK1 Recombinant Protein (RPES4301)

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SKU:
RPES4301
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Kallikrein 1/KLK1 Recombinant Protein

Human tissue kallikrein (KLK1) is a serine protease, component of the KKS that has been demonstrated to exert pleiotropic beneficial effects in protection from tissue injury through its antiinflammatory, antiapoptotic, antifibrotic and antioxidative actions.Polymorphism of the human tissue kallikrein 1 (KLK1) A1789G gene is associated with susceptibility to hypertension.

Product Name:Human Kallikrein 1/KLK1 Recombinant Protein (RPES4301)
Product Code:RPES4301
Size:10µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:Kallikrein-1, Kidney/Pancreas/Salivary Gland Kallikrein, Tissue Kallikrein, KLK1
Accession:NP_002248.1
Sequence:Met 1-Ser 262
Fusion tag:C-His
Activity:Measured by its ability to cleave a flourogenic peptide substrate Pro-Phe-Arg-7-amido-4-methylcoumarin (PFR-AMC). The specific activity is >1,500 pmoles/min/µg.(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)
Endotoxin:<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human KLK1 (NP_002248.1) precursor (Met 1-Ser 262) was expressed with a polyhistidine tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:28 kDa
AP Mol Mass:50 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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