Human JNK ELISA Kit

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SKU:
HUFI02082
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P45983
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
MAPK8, PRKM8, SAPK1, c-Jun N-terminal kinase 1, JNK1 alpha protein kinase, JNK1 beta protein kinase, JNK1JNK1A2, JNK-46, JUN N-terminal kinase, MAP kinase 8, MAPK 8, mitogen-activated protein kinase 8, mitogen-activated protein kinase 8 isoform JNK1
Reactivity:
Human

Description

Human JNK ELISA Kit

MAPK8 (Mitogen-Activated Protein Kinase 8) encodes a member of the Ser/Thr protein kinase family, whose members are activated by mitogenic stimuli and contribute to the regulation of cell proliferation, differentiation and apoptosis through control of the transcription factor NF-kappaB. MAPK8 is overexpressed in breast cancers as well as endometrial adenocarcinomas and myeloid leukemia cell lines. MAPK8 associates with SHP2, which may provide a link to the Vav family of guanine nucleotide exchange factors for Ras proteins. An important paralog of MAPK8 is MAPK8IP2.

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