Human JAM2 Recombinant Protein (RPPB3765)

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SKU:
RPPB3765
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P57087

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human JAM2 Recombinant Protein
Product Code:RPPB3765
Size:10µg
Species:Human
Target:JAM2
Synonyms:Junctional Adhesion Molecule 2, Vascular Endothelial Junction-Associated Molecule, C21orf43, VE-JAM, JAM-2, JAM-B, VEJAM, Junctional Adhesion Molecule B, JAM-IT/VE-JAM, CD322 Antigen, PRO245, CD322, JAMB, Junctional adhesion molecule B.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:JAM2 protein solution (0.5mg/ml) contains 50% glycerol, 1mM DTT & Phosphate Buffered Saline (pH 7.4).
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:ADPFSAPKDQ QVVTAVEYQE AILACKTPKK TVSSRLEWKK LGRSVSFVYY QQTLQGDFKN RAEMIDFNIR IKNVTRSDAG KYRCEVSAPS EQGQNLEEDT VTLEVLVAPA VPSCEVPSSA LSGTVVELRC QDKEGNPAPE YTWFKDGIRL LENPRLGSQS TNSSYTMNTK TGTLQFNTVS KLDTGEYSCE ARNSVGYRRC PGKRMQVDDL NISLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN�QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH

Junctional Adhesion Molecule 2 (JAM2) is a member of the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. JAM2 is a type I membrane protein which is localized at the tight junctions of both epithelial and endothelial cells. JAM2 functions as an adhesive ligand for interacting with various immune cell types, and may have a role in lymphocyte homing to secondary lymphoid organs.

JAM2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 452 amino acids (29-238a.a.) and having a molecular mass of 50.7kDa. (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).JAM2 is expressed with a 239 amino acid hIgG-His-tag at C-Terminus and purified by proprietary chromatographic techniques.

UniProt Protein Function:May play a role in the processes of lymphocyte homing to secondary lymphoid organs.
NCBI Summary:This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]
UniProt Code:P57087
NCBI GenInfo Identifier:10720348
NCBI Gene ID:58494
NCBI Accession:P57087.1
UniProt Secondary Accession:P57087,Q6UXG6, Q6YNC1, B2R6T9, B4DGT9,
UniProt Related Accession:P57087
Molecular Weight:34,554 Da
NCBI Full Name:Junctional adhesion molecule B
NCBI Synonym Full Names:junctional adhesion molecule 2
NCBI Official Symbol:JAM2��
NCBI Official Synonym Symbols:JAMB; CD322; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43��
NCBI Protein Information:junctional adhesion molecule B
UniProt Protein Name:Junctional adhesion molecule B
UniProt Synonym Protein Names:Junctional adhesion molecule 2; JAM-2; Vascular endothelial junction-associated molecule; VE-JAM; CD_antigen: CD322
Protein Family:Junctional adhesion molecule
UniProt Gene Name:JAM2��
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system_update_altDatasheetMouse JAM2/CD322 Recombinant Protein Junctional adhesion molecule B (JAM-B), also known as Junctional adhesion molecule 2 (JAM2), Vascular endothelial junction-associate