Human JAM2 Recombinant Protein (RPPB3764)
- SKU:
- RPPB3764
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P57087
Description
| Product Name: | Human JAM2 Recombinant Protein |
| Product Code: | RPPB3764 |
| Size: | 20µg |
| Species: | Human |
| Target: | JAM2 |
| Synonyms: | Junctional adhesion molecule B, JAM-B, Junctional adhesion molecule 2, JAM-2, Vascular endothelial junction-associated molecule, VE-JAM, CD322. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | JAM2 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.4M urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSLGYHKAY GFSAPKDQQV VTAVEYQEAI LACKTPKKTV SSRLEWKKLG RSVSFVYYQQ TLQGDFKNRA EMIDFNIRIK NVTRSDAGKY RCEVSAPSEQ GQNLEEDTVT LEVLVAPAVP SCEVPSSALS GTVVELRCQD KEGNPAPEYT WFKDGIRLLE NPRLGSQSTN SSYTMNTKTG TLQFNTVSKL DTGEYSCEAR NSVGYRRCPG KRMQVDDLNI S |
Junctional Adhesion Molecule 2 (JAM2) is a member of the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. JAM2 is a type I membrane protein which is localized at the tight junctions of both epithelial and endothelial cells. JAM2 functions as an adhesive ligand for interacting with various immune cell types, and may have a role in lymphocyte homing to secondary lymphoid organs.
JAM2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 241 amino acids (21-238) and having a molecular mass of 26.7kDa. JAM2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | May play a role in the processes of lymphocyte homing to secondary lymphoid organs. |
| NCBI Summary: | This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | P57087 |
| NCBI GenInfo Identifier: | 10720348 |
| NCBI Gene ID: | 58494 |
| NCBI Accession: | P57087.1 |
| UniProt Secondary Accession: | P57087,Q6UXG6, Q6YNC1, B2R6T9, B4DGT9, |
| UniProt Related Accession: | P57087 |
| Molecular Weight: | 34,554 Da |
| NCBI Full Name: | Junctional adhesion molecule B |
| NCBI Synonym Full Names: | junctional adhesion molecule 2 |
| NCBI Official Symbol: | JAM2�� |
| NCBI Official Synonym Symbols: | JAMB; CD322; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43�� |
| NCBI Protein Information: | junctional adhesion molecule B |
| UniProt Protein Name: | Junctional adhesion molecule B |
| UniProt Synonym Protein Names: | Junctional adhesion molecule 2; JAM-2; Vascular endothelial junction-associated molecule; VE-JAM; CD_antigen: CD322 |
| Protein Family: | Junctional adhesion molecule |
| UniProt Gene Name: | JAM2�� |
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