Human JAK1 ELISA Kit

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SKU:
HUFI02149
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P23458
Sensitivity:
0.469ng/ml
Range:
0.781-50ng/ml
ELISA Type:
Sandwich
Synonyms:
JAK1, Janus Kinase 1, EC 2.7.10, JAK-1, JAK1Atyrosine-protein kinase JAK1, JAK1B, Janus kinase 1EC 2.7.10.2, JTK3
Reactivity:
Human
Research Area:
Cell Biology

Description

Human JAK1 ELISA

JAK1 (Janus Kinase 1) phosphorylates STAT proteins and plays a key role in interferon signal transduction. JAK1 plays a crucial role in effecting the expression of genes that mediate inflammation, epithelial remodeling, and metastatic cancer progression. JAK1 is a key component of the interleukin-6 (IL-6)/JAK1/STAT3 immune and inflammation response and is a therapeutic target for alleviating cytokine storms. JAK1 deficiency causes increased susceptibility to mycobacterial diseases, and is associated with autoinflammation and eosinophilia.

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