Izumo sperm-egg fusion protein 4 is a sperm membrane protein which plays a key role in the fusion in the mouse. IZUMO4 has an N-terminal domain with significant homology to the N-terminal domain of Izumo.It belongs to the Izumo family . Izumo 4 is a soluble protein expressed in the testis and in other tissues. Izumo domain possesses the ability to form dimers; whereas the transmembrane domain or the cytoplasmic domain or both of Izumo 1 are required for the formation of multimers of higher order.
Product Name:
Human IZUMO4 Recombinant Protein (RPES1570)
Product Code:
RPES1570
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
C19orf36,IMAGE:4215339,UNQ831/PRO1758
Accession:
Q1ZYL8
Sequence:
His16-His214
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Izumo sperm-egg fusion protein 4 is produced by our Mammalian expression system and the target gene encoding His16-His214 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
50.1 kDa
AP Mol Mass:
60 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.