Immunology Recombinant Proteins

Human IRF5 Recombinant Protein (RPES1741)

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SKU:
RPES1741
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

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Human IRF5 Recombinant Protein

Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.

Product Name:Human IRF5 Recombinant Protein (RPES1741)
Product Code:RPES1741
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Interferon Regulatory Factor 5, IRF-5, IRF5
Accession:Q13568
Sequence:Met 1-Gln498
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Interferon Regulatory Factor 5 is produced by our E.coli expression system and the target gene encoding Met1-Gln498 is expressed with a 6His tag at the C-terminus.
Purity:> 90 % as determined by reducing SDS-PAGE.
Mol Mass:57.1 kDa
AP Mol Mass:60 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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