Human INTS3 / Integrator complex subunit 3 ELISA Kit

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SKU:
HUFI00603
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q68E01
Sensitivity:
46.875pg/ml
Range:
78.125-5000pg/ml
ELISA Type:
Sandwich
Synonyms:
INTS3, IntegRator complex subunit 3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, SOSS-A, Sensor of ssDNA subunit A
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human INTS3 / Integrator complex subunit 3 ELISA Kit

INTS3 / Integrator complex subunit 3 is part of a multiprotein complex that interacts with the C-terminal domain of RNA polymerase II large subunit to help regulate processing of U1 and U2 small nuclear RNAs. INTS3 / Integrator complex subunit 3 can form a complex with human single-strand DNA binding proteins 1 or 2 (hSSB1 and hSSB2) and other proteins to mediate genome stability and the DNA damage response. Autosomal Dominant Non-Syndromic Intellectual Disability is one of the diseases associated with INTS3 / Integrator complex subunit 3.

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