Human IMP3 Recombinant Protein (RPPB3747)
- SKU:
- RPPB3747
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NV31
Description
| Product Name: | Human IMP3 Recombinant Protein |
| Product Code: | RPPB3747 |
| Size: | 20µg |
| Species: | Human |
| Target: | IMP3 |
| Synonyms: | BRMS2, C15orf12, MRPS4, U3 snoRNP protein IMP3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | IMP3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMVRKLKF HEQKLLKQVD FLNWEVTDHN LHELRVLRRY RLQRREDYTR YNQLSRAVRE LARRLRDLPE RDQFRVRASA ALLDKLYALG LVPTRGSLEL CDFVTASSFC RRRLPTVLLK LRMAQHLQAA VAFVEQGHVR VGPDVVTDPA FLVTRSMEDF VTWVDSSKIK RHVLEYNEER DDFDLEA |
IMP3 is the human homolog of the yeast Imp3 protein and Essential for the early cleavages during pre-18S ribosomal RNA processing. IMP3 is a Part of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). IMP3 is a member of to the ribosomal protein S4P family and localizes to the nucleoli and interacts with the U3 snoRNP complex. IMP3 contains an S4 domain. U3 small nucleolar ribonucleoprotein protein IMP3 is a protein which in humans is encoded by the IMP3 gene.
IMP3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (1-184 a.a) and having a molecular mass of 24kDa. IMP3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | IMP3: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. Belongs to the ribosomal protein S4P family.Protein type: Nucleolus; RNA processing; RNA-bindingChromosomal Location of Human Ortholog: 15q24Cellular Component: nucleolus; nucleoplasm; nucleus; small ribosomal subunit; small subunit processomeMolecular Function: protein binding; rRNA binding; snoRNA binding; structural constituent of ribosomeBiological Process: positive regulation of translational fidelity; rRNA processing |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NV31 |
| NCBI GenInfo Identifier: | 52783099 |
| NCBI Gene ID: | 55272 |
| NCBI Accession: | Q9NV31.1 |
| UniProt Secondary Accession: | Q9NV31,Q53G10, B3KQ67 |
| UniProt Related Accession: | Q9NV31 |
| Molecular Weight: | 21,850 Da |
| NCBI Full Name: | U3 small nucleolar ribonucleoprotein protein IMP3 |
| NCBI Synonym Full Names: | IMP3, U3 small nucleolar ribonucleoprotein |
| NCBI Official Symbol: | IMP3�� |
| NCBI Official Synonym Symbols: | BRMS2; MRPS4; C15orf12�� |
| NCBI Protein Information: | U3 small nucleolar ribonucleoprotein protein IMP3 |
| UniProt Protein Name: | U3 small nucleolar ribonucleoprotein protein IMP3 |
| UniProt Synonym Protein Names: | BRMS2 |
| Protein Family: | U3 small nucleolar ribonucleoprotein protein |
| UniProt Gene Name: | IMP3�� |
| UniProt Entry Name: | IMP3_HUMAN |
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