Immune Checkpoint Recombinant Proteins
Human IL6R Recombinant Protein (His Tag) (HDPT0125)
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- SKU:
- HDPT0125
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human IL6R Recombinant Protein (His Tag)
| Description: | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9. |
| Product name: | Human IL6R Recombinant Protein (His Tag) |
| Synonyms: | CD126; gp80; IL-6R-1; IL-6RA; IL6Q; IL6RA; IL6RQ |
| Type: | protein |
| Size: | 50 µg |
| Name: | IL6R |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | ELISA |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | IL6R(Leu20-Pro365)+6×His tag |
| Gene ID: | 3570 |
| Uniprot: | P08887 |
| Molecular Weight: | 55-70 kDa |
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