Immune Checkpoint Recombinant Proteins

Human IL6R Recombinant Protein (hFc Tag) (HDPT0182)

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SKU:
HDPT0182
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human IL6R Recombinant Protein (hFc Tag)

Description:This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Product name:Human IL6R Recombinant Protein (hFc Tag)
Synonyms:CD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ
Type:protein
Size:50 µg
Name:IL6
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:IL6R(Leu20-Pro365)+hFc(Glu99-Ala330)
Gene ID:3569
Uniprot:P08887
Molecular Weight:70-100 kDa
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