Cytokines Recombinant Proteins

Human IL6 Recombinant Protein (RPPB0526)

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SKU:
RPPB0526
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P05231
Research Area:
Cytokines

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human IL6 Recombinant Protein
Product Code:RPPB0526
Size:10µg
Species:Human
Target:IL6
Synonyms:BSF2, HGF, HSF, IFNB2, IL-6.
Source:Sf9 Insect cells
Physical Appearance:Sterile Filtered colorless solution.
Formulation:IL6 protein (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENNLNLPKMAEKD GCFQSGFNEE TCLVKIITGL LEFEVYLEYL QNRFESSEEQ ARAVQMSTKVLIQFLQKKAK NLDAITTPDP TTNASLLTKL QAQNQWLQDM TTHLILRSFK EFLQSSLRAL RQMHHHHHH
Biological Activity:The ED50, determined by cell proliferation assay using TF-1 human erythroleukemic cell, is 0.2 - 0.8 ng/ml .�

Interleukin-6 or Il-6 is a cytokine with a large assortment of biological functions. IL-6 it has a crucial part in the last differentiation of b-cells into ig-secreting cells. This cytokine also induces myeloma and plasmacytoma growth. Interleukin-6 induces nerve cells differentiation, among hepatocytes it induces acute phase reactants.

IL6 Human Recombinant produced in Baculovirus is a single glycosylated polypeptide chain containing 189 amino acids (30-212aa) and having a molecular mass of 21.6kDa.(Migrates at 18-28kDa on SDS-PAGE under reducing conditions).IL6 is fused to a 6 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.

UniProt Code:P05231
NCBI GenInfo Identifier:124347
NCBI Gene ID:3569
NCBI Accession:P05231.1
UniProt Secondary Accession:P05231,Q9UCU2, Q9UCU3, Q9UCU4,
UniProt Related Accession:P05231
Molecular Weight:212
NCBI Full Name:Interleukin-6
NCBI Synonym Full Names:interleukin 6
NCBI Official Symbol:IL6��
NCBI Official Synonym Symbols:HGF; HSF; BSF2; IL-6; IFNB2��
NCBI Protein Information:interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor
UniProt Protein Name:Interleukin-6
UniProt Synonym Protein Names:B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2
Protein Family:Interleukin
UniProt Gene Name:IL6��
UniProt Entry Name:IL6_HUMAN
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