Immunology Recombinant Proteins
Human IL2RG/CD132 Recombinant Protein (RPES3703)
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- SKU:
- RPES3703
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immunology
Description
system_update_altDatasheet
Human IL2RG/CD132 Recombinant Protein
IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors; including those of interleukin -2; -4; -7 and -21; and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).
| Product Name: | Human IL2RG/CD132 Recombinant Protein (RPES3703) |
| Product Code: | RPES3703 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Cytokine receptor common subunit gamma, Interleukin-2 receptor subunit gamma, gammaC, P64, CD132, IL2RG, SCIDX,SCIDX1, CIDX |
| Accession: | P31785 |
| Sequence: | Leu23-Ala262 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Cytokine receptor common subunit gamma is produced by our Mammalian expression system and the target gene encoding Leu23-Ala262 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 55.4 kDa |
| AP Mol Mass: | 85-100 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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