Immune Checkpoint Recombinant Proteins

Human IL2RB Recombinant Protein (His Tag) (HDPT0059)

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SKU:
HDPT0059
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human IL2RB Recombinant Protein (His Tag)

Description:The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.
Product name:Human IL2RB Recombinant Protein (His Tag)
Synonyms:IL2RB,RP5-1170K4.6,CD122,P70-75
Type:protein
Size:50 µg
Name:IL2RB
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:IL2RB（Ala27-Asp239）+6×His tag
Gene ID:3560
Uniprot:P14784
Molecular Weight:25.4 kDa
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