Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane protein; contains 2 Sushi (CCP/SCR) domains. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains; together with the common gamma chain (IL2RG); constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor; while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein; soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.
Recombinant Human IL2Ra is produced by our Mammalian expression system and the target gene encoding Glu22-Cys213 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
22.8 kDa
AP Mol Mass:
40 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
system_update_altDatasheetHuman IL2Ra/CD25 Recombinant Protein CD25 (alpha-chain of IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region
system_update_altDatasheetHuman IL2Ra/CD25 Recombinant Protein Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane protein; contains 2 Sushi (CCP/SCR) domains. The inter
system_update_altDatasheetMouse IL2Ra/CD25 Recombinant Protein The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, ac
system_update_altDatasheetMouse IL2Ra/CD25 Recombinant Protein The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, ac
system_update_altDatasheetMouse IL2Ra/CD25 Recombinant Protein CD25 (alpha-chain of IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region