Growth Factors & Cytokines Recombinant Proteins

Human IL2Ra/CD25 Recombinant Protein (RPES1153)

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RPES1153

Description

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Human IL2Ra/CD25 Recombinant Protein

Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane protein; contains 2 Sushi (CCP/SCR) domains. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains; together with the common gamma chain (IL2RG); constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor; while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein; soluble IL2RA has been isolated and determined to result from extracellular proteolyisis.

Product Name:Human IL2Ra/CD25 Recombinant Protein (RPES1153)
Product Code:RPES1153
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Interleukin-2 receptor subunit alpha,CD25,p55,TAC antigen,IL2-RA,IL-2R subunit alpha,IL-2-RA,IL-2 receptor subunit alpha, IL-2R?,IDDM10,IL2R,p55,TCGFR
Accession:P01589
Sequence:Glu22-Cys213
Fusion tag:C-Fc
Activity:Immobilized Human IL-2RA-Fc at 10µg/ml(100 ?l/well) can bind Human IL-2-His(Cat: PKSH032629). The ED50 of Human IL-2RA-Fc is 0.46 ug/mL
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Interleukin-2 Receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Cys213 is expressed with a Fc tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:48.9 kDa
AP Mol Mass:60-90 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Growth Factors & Cytokines
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