Immune Checkpoint Recombinant Proteins

Human IL1B Recombinant Protein (hFc Tag) (HDPT0238)

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SKU:
HDPT0238
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human IL1B Recombinant Protein (hFc Tag)

Description:The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Product name:Human IL1B Recombinant Protein (hFc Tag)
Synonyms:IL-1; IL1-BETA; IL1F2
Type:protein
Size:50 µg
Name:IL1B
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:IL1B (Ala117-Ser269)+hFc(Glu99-Ala330)
Gene ID:
Uniprot:P01584
Molecular Weight:42.35 kDa
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