Immune Checkpoint Recombinant Proteins
Human IL1B Recombinant Protein (hFc Tag) (HDPT0238)
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- SKU:
- HDPT0238
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human IL1B Recombinant Protein (hFc Tag)
| Description: | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
| Product name: | Human IL1B Recombinant Protein (hFc Tag) |
| Synonyms: | IL-1; IL1-BETA; IL1F2 |
| Type: | protein |
| Size: | 50 µg |
| Name: | IL1B |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | Contact Technical Support |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | IL1B (Ala117-Ser269)+hFc(Glu99-Ala330) |
| Gene ID: | |
| Uniprot: | P01584 |
| Molecular Weight: | 42.35 kDa |
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