Immune Checkpoint Recombinant Proteins
Human IL17RA Recombinant Protein (His Tag) (HDPT0081)
- SKU:
- HDPT0081
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human IL17RA Recombinant Protein (His Tag)
| Description: | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Product name: | Human IL17RA Recombinant Protein (His Tag) |
| Synonyms: | CD217,CDw217,IL-17RA,IL17R,CANDF5,hIL-17R |
| Type: | protein |
| Size: | 50 µg |
| Name: | IL17RA |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C- 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | IL17RA(Leu33-Trp320)+6×His tag |
| Gene ID: | 23765 |
| Uniprot: | Q96F46 |
| Molecular Weight: | 34.3 kDa |