Immune Checkpoint Recombinant Proteins
Human IL15RA Recombinant Protein (hFc Tag) (HDPT0195)
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- SKU:
- HDPT0195
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human IL15RA Recombinant Protein (hFc Tag)
| Description: | This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. |
| Product name: | Human IL15RA Recombinant Protein (hFc Tag) |
| Synonyms: | CD215 |
| Type: | protein |
| Size: | 50 µg |
| Name: | IL15RA |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | IL15RA（Ile31-Thr205）+hFc（Glu99-Ala330） |
| Gene ID: | 3601 |
| Uniprot: | Q13261 |
| Molecular Weight: | 70 kDa |
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