Growth Factors & Cytokines Recombinant Proteins
Human IL0/Interleukin0 Recombinant Protein (RPES1347)
- SKU:
- RPES1347
Description
Human IL0/Interleukin0 Recombinant Protein
Interleukin 10(IL10), also known as cytokine synthesis inhibitory factor (CSIF),is a secreted protein andbelongs to the IL-10 family. IL-10 is produced by a variety of activated hematopoietic cell types, as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts. IL-10 is an anti-inflammatory TH2 cytokinethat has a key function in inhibiting the host's immune response, preventing damage. Many T helper cells are inactivated by IL-10, which is suggested to act as a feedback loop that restricts macrophage and DC effector activities on T cells. STAT3 is activated by IL-10 through the IL-10 receptor (IL-10 R) after it has been released. IL-10 is a potent anti-inflammatory cytokine that has established itself as an important indicator for numerous diseases and ailments, as well as a therapeutic drug for several illnesses. High amounts of IL-10 are also present in viral infections that cause immunodeficiency, particularly retroviral infections. IL-10's immunosuppressive qualities suggest that it may be used in the treatment of organ transplant rejection. Human IL0/Interleukin0 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human IL0/Interleukin0 Recombinant Protein (RPES1347) |
| Product Code: | RPES1347 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10, RP11-262N9.1, IL10A, MGC126450, MGC126451, TGIF |
| Accession: | P22301 |
| Sequence: | Ser19-Asn178 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Interleukin-10 is produced by our Mammalian expression system and the target gene encoding Ser19-Asn178 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 19.6 kDa |
| AP Mol Mass: | 16 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Growth Factors & Cytokines |