Cytokines Recombinant Proteins
Human IL 6 Recombinant Protein (RPPB0522)
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- SKU:
- RPPB0522
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P05231
- Research Area:
- Cytokines
Description
| Product Name: | Human IL 6 Recombinant Protein |
| Product Code: | RPPB0522 |
| Size: | 20µg |
| Species: | Human |
| Target: | IL 6 |
| Synonyms: | B cell differentiation factor, BCDF, BSF-2, HPGF, HSF, MGI-2, B-cell stimulatory factor 2,Hybridoma growth factor, CTL differentiation factor, CDF, IL-6, HGF. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Lyophilized from a 0.2um filtered concentrated (1mg/ml) solution in PBS, pH 7.4. |
| Solubility: | It is recommended to reconstitute the lyophilized Interleukin-6 in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Interleukin-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL6 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | The sequence of the first five N-terminal amino acids was determined and was found to be Met-Pro-Val-Pro-Pro |
| Biological Activity: | The ED50 as determined by the dose-dependant stimulation of murine 7TD1 cells is less than 0.1 ng/ml, corresponding to the specific activity of 1.0 x 10,000,000 Units per mg. |
Il-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of b-cells into ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants.
Interleukin-6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 21000 Dalton. The IL6 is purified by proprietary chromatographic techniques.
| UniProt Code: | P05231 |
| NCBI GenInfo Identifier: | 124347 |
| NCBI Gene ID: | 3569 |
| NCBI Accession: | P05231.1 |
| UniProt Secondary Accession: | P05231,Q9UCU2, Q9UCU3, Q9UCU4, |
| UniProt Related Accession: | P05231 |
| Molecular Weight: | 212 |
| NCBI Full Name: | Interleukin-6 |
| NCBI Synonym Full Names: | interleukin 6 |
| NCBI Official Symbol: | IL6�� |
| NCBI Official Synonym Symbols: | HGF; HSF; BSF2; IL-6; IFNB2�� |
| NCBI Protein Information: | interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon, beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor |
| UniProt Protein Name: | Interleukin-6 |
| UniProt Synonym Protein Names: | B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL6�� |
| UniProt Entry Name: | IL6_HUMAN |
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