Immunology Recombinant Proteins

Human IL-2RB/CD122 Recombinant Protein (RPES1189)

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SKU:
RPES1189
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

system_update_altDatasheet

Human IL-2RB/CD122 Recombinant Protein

Human IL-2RB; also known asinterleukin-2 receptor subunit beta;is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein;and has a 26 residue signal peptide; a 214 residue extracellular region; a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules; such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.

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