Human IL-20RA/IL-20R1 Recombinant Protein (RPES1257)

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SKU:
RPES1257
Product Type:
Recombinant Protein
Species:
Human

Description

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Human IL-20RA/IL-20R1 Recombinant Protein

Interleukin-20 Receptor Subunit ? (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide; a 221 amino acid extracellular domain with two fibronectin type-III domains; a 24 amino acid transmembrane region; and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB; and the complex serves as a receptor for IL19; IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.

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