Description
Product Name: | Human IL-1Ra Recombinant Protein |
Product Code: | RPES6543 |
Size: | 20μg |
Species: | Human |
Expression Host: | E.coli |
Synonyms: | Interleukin-1 receptor antagonist protein,IL-1RN,IL-1ra,IRAP,ICIL-1RA,IL1 inhibitor,Anakinra,IL1RN,IL1F3,IL1RA |
Mol Mass: | 19.4 kDa |
AP Mol Mass: | 19 kDa |
Tag: | N-His |
Purity: | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin Level: | Please contact us for more information. |
Bio Activity: | Testing in progress |
Sequence: | Arg26-Glu177 |
Accession: | P18510 |
Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation: | Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the print |
Reconstitution: | Please refer to the printed manual for detailed information. |
Background: | Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. |