Human IgG4/Immunoglobulin heavy constant gamma 4 Polyclonal Antibody

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SKU:
CAB24655
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB

Description

Product Name:Human IgG4/Immunoglobulin heavy constant gamma 4 Polyclonal Antibody
Product Code:CAB24655
Reactivity:Human
Applications:Western blotting
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Reactivity:Human
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Positive Samples:RPMI-8226, SH-SY5Y, Daudi, U-251 MG, K-562
Cellular Location:Secreted

Immunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IgG4/Immunoglobulin heavy constant gamma 4 (P01861).
Sequence:VHTFP AVLQS SGLYS LSSVV TVPSS SLGTK TYTCN VDHKP SNTKV DKRVE SKYGP PCPSC PAPEF LGGPS VFLFP PKPKD TLMIS RTPEV TCVVV DVSQE D
Synonyms:IGHG4, Ig gamma-4 chain C region
Calculated MW:44kDa
Observed MW:36kDa
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