Description
Product Name: | Human IgG3 Monoclonal Antibody |
Product Code: | CAB23914 |
Reactivity: | Human |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC62453 |
Reactivity: | Human |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | IGHG3 Recombinant proteins |
Cellular Location: | Secreted, Cell membrane, Single-pass membrane protein |
Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Involved in retina homeostasis. Located in blood microparticle and extracellular exosome.IgG is a monomeric immunoglobulin, built of two heavy chains gamma and two light chains. Each molecule has two antigen binding sites. This is the most abundant immunoglobulin and is approximately equally distributed in blood and in tissue liquids, constituting 75% of serum immunoglobulins in humans. There are 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%).
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-167 of human IgG3 (P01860). |
Sequence: | ELKTP LGDTT HTCPR CPEPK SCDTP PPCPR CPEPK SCDTP PPCPR CPEPK SCDTP PPCPR CPAPE LLGGP SVFLF PPK |
Synonyms: | IgG3 |
Calculated MW: | 41KDa/49KDa |
Observed MW: | 68kDa |