Human IGF 1R / IGF 1 receptor ELISA Kit

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SKU:
HUFI01103
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P08069
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
IGF1R, CD221, IGF-I R, IGFR, JTK13, CD221 antigen, IGF-I receptor, Insulin-like growth factor I receptor, soluble IGF1R variant 1, soluble IGF1R variant 2
Reactivity:
Human
Research Area:
Cell Biology

Description

Human IGF 1R / IGF 1 receptor ELISA Kit

IGF 1R/IGF 1 receptor has a high affinity for insulin-like growth factor. It functions as a tyrosine kinase. In transformation processes, the insulin-like growth factor I receptor is crucial. The precursor is cleaved into alpha and beta subunits. It is overexpressed in the majority of malignant tissues, where it acts as an anti-apoptotic agent by promoting cell survival. IGF 1R/IGF 1 receptor has alternatively spliced transcript variants that encode different isoforms. Insulin-Like Growth Factor I and Nk-Cell Enteropathy are two diseases linked to IGF1R. Actin Nucleation by ARP-WASP Complex and the CREB Pathway are related pathways.

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