Human IgA1 Monoclonal Antibody (CAB24333)
- SKU:
- CAB24333
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- FC
Description
| Product Name: | Human IgA1 Monoclonal Antibody |
| Product Code: | CAB24333 |
| Reactivity: | Human |
| Applications: | Western blotting, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60386 |
| Reactivity: | Human |
| Tested Applications: | WB, FC, ELISA |
| Key Applications: | Western blotting, Flow Cytometry |
| Recommended Dilution: | WB 1:1000-1:5000, FC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Human plasma |
| Cellular Location: | Blood microparticle, extracellular exosome, extracellular region, extracellular space, plasma membrane |
Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. In normal adult serum, the approximate percentage composition of IgA with respect to is subclasses is IgA1:90% and IgA2:10%. In secretory IgA, the subclass proportions may approach 50:50. The clinical significance of the subclasses has yet to be determined.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-353 of human IgA1. |
| Sequence: | VPCPV PSTPP TPSPS TPPTP SPSCC HPRLS LHRPA LEDLL LGSEA NLTCT LTGLR DASGV TFTWT PSSGK SAVQG PPERD LCGCY SVSSV LPGCA EPWNH GKTFT CTAAY PESKT PLTAT LSKSG NTFRP EVHLL PPPSE ELALN ELVTL TCLAR GFSPK DVLVR WLQGS QELPR EKYLT WASRQ EPSQG TTTFA VTSIL RVAAE DWKKG DTFSC MVGHE ALPLA FTQKT IDRLA DWQMP PPYVV LDLPQ ETLEE |
| Synonyms: | IgA1 |
| Calculated MW: | 42kDa |
| Observed MW: | 55kDa |
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