Human IgA / Immunoglobulin A ELISA Kit

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SKU:
HUFI00328
Product Type:
ELISA Kit
Size:
96 Assays
Sensitivity:
1.875ng/ml
Range:
3.125-200ng/ml
ELISA Type:
Sandwich
Synonyms:
IgA, Immunoglobulin A
Reactivity:
Human
Research Area:
Immunology

Description

Human IgA / Immunoglobulin A ELISA Kit

IgA / Immunoglobulin A is a protein which is necessary for surface expression and function of the B-cell antigen receptor. IgA / Immunoglobulin A plays a role in initiation of the signal transduction cascade by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. IgA / Immunoglobulin A is required for efficient differentiation of pro- and pre-B-cells, and represses BCR signaling during development of immature B-cells. Deficiency in IgA / Immunoglobulin A is linked to a disease known as Agammaglobulinemia.

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