Human IFNAR1 Recombinant Protein (His Tag) (RPES6177)

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SKU:
RPES6177

Description

Product Name:Human IFNAR1 Recombinant Protein (His Tag)
Product Code:RPES6177
Size:20µg
Species:Human
Expression Host:E.coli
Synonyms:Interferon alpha/beta receptor 1, IFN-R-1 IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR
Application:Immunogen
Mol Mass:20 kDa
AP Mol Mass:22.3 kDa
Tag:N-His
Purity:> 85 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Lys28-Leu200
Accession:P17181-1
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2 . Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
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