Cytokines Recombinant Proteins

Human IFNA2C Recombinant Protein (RPPB5731)

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SKU:
RPPB5731
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P01563
Research Area:
Cytokines

Description

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Product Name:Human IFNA2C Recombinant Protein
Product Code:RPPB5731
Size:100µg
Species:Human
Target:IFNA2C
Synonyms:Interferon alpha-2, IFN-alpha-2, Interferon alpha-A, LeIF A, IFNA2, IFNA2A, IFNA2B, IFNA2C.
Source:Saccharomyces cerevisiae
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:Lyophilized from a 0.2?m filtered concentrated solution in PBS, pH 7.4 and 0.02 % Tween-20.
Solubility:It is recommended to reconstitute the lyophilized Interferon-alpha 2c in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions.
Stability:Lyophilized IFNA2C although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Interferon-alpha 2c should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Purity:Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Amino Acid Sequence:CDLPQTHSLG SRRTLMLLAQ MRRISLFSCL KDRRDFGFPQ EEFGNQFQKA ETIPVLHEMI QQIFNLFSTK DSSAAWDETL LDKFYTELYQ QLNDLEACVI QGVGVTETPL MKEDSILAVR KYFQRITLYL KEKKYSPCAW EVVRAEIMRS FSLSTNLQES LRSKE
Biological Activity:The activity is determined by the cytopathic effect inhibition assay.�

IFN-alpha is produced by macrophages and has antiviral activities. IFN stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.

Interferon-alpha 2c Recombinant Human produced in yeast is a single, glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of 19.3kDa. The IFNA2C is purified by proprietary chromatographic techniques.

UniProt Protein Function:Produced by macrophages, IFN-alpha have antiviral activities.
NCBI Summary:This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011]
UniProt Code:P01563
NCBI GenInfo Identifier:124449
NCBI Gene ID:3440
NCBI Accession:P01563.1
UniProt Secondary Accession:P01563,P01564, Q14606, Q6DJX8, Q96KI6, H2DF54, H2DF55
UniProt Related Accession:P01563
Molecular Weight:21,550 Da
NCBI Full Name:Interferon alpha-2
NCBI Synonym Full Names:interferon alpha 2
NCBI Official Symbol:IFNA2��
NCBI Official Synonym Symbols:IFNA; INFA2; IFNA2B; IFN-alphaA��
NCBI Protein Information:interferon alpha-2
UniProt Protein Name:Interferon alpha-2
UniProt Synonym Protein Names:Interferon alpha-A; LeIF A
UniProt Gene Name:IFNA2��
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