Cytokines Recombinant Proteins
Human IFNA14 Recombinant Protein (RPPB0390)
- SKU:
- RPPB0390
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P01570
- Research Area:
- Cytokines
Description
| Product Name: | Human IFNA14 Recombinant Protein |
| Product Code: | RPPB0390 |
| Size: | 20µg |
| Species: | Human |
| Target: | IFNA14 |
| Synonyms: | Interferon alpha-14, IFN-alpha-14, Interferon alpha-H, LeIF H, Interferon lambda-2-H, IFNA14, LEIF2H, IFN-alphaH. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | IFNA14 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 50% glycerol, 0.2M NaCl and 2mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMCNLSQ THSLNNRRTL MLMAQMRRIS PFSCLKDRHD FEFPQEEFDG NQFQKAQAIS VLHEMMQQTF NLFSTKNSSA AWDETLLEKF YIELFQQMND LEACVIQEVG VEETPLMNED SILAVKKYFQ RITLYLMEKK YSPCAWEVVR AEIMRSLSFS TNLQKRLRRK D |
Interferon alpha-14 (IFNA14) is a member of the alpha/beta interferon family. IFNA14 is produced by macrophages (IFN-alpha have antiviral activities). The interferon stimulates the production of 2 enzymes: a protein kinase and an oligoadenylate synthetase.
IFNA14 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 191 amino acids (24-189 a.a.) and having a molecular mass of 22.4kDa.IFNA14 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | IFNA14: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Belongs to the alpha/beta interferon family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Membrane protein, integral Chromosomal Location of Human Ortholog: 9p22 Cellular Component: extracellular space; extracellular region Molecular Function:hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein |
| UniProt Code: | P01570 |
| NCBI GenInfo Identifier: | 170763491 |
| NCBI Gene ID: | 3448 |
| NCBI Accession: | NP_002163.2 |
| UniProt Secondary Accession: | P01570,P01566, P05014, P01567, |
| UniProt Related Accession: | P01570 |
| Molecular Weight: | 22,063 Da |
| NCBI Full Name: | interferon alpha-14 |
| NCBI Synonym Full Names: | interferon, alpha 14 |
| NCBI Official Symbol: | IFNA14�� |
| NCBI Official Synonym Symbols: | LEIF2H; IFN-alphaH�� |
| NCBI Protein Information: | interferon alpha-14; IFN-alpha-14; interferon alpha-H; interferon lambda-2-H; leIF H |
| UniProt Protein Name: | Interferon alpha-14 |
| UniProt Synonym Protein Names: | Interferon alpha-H; LeIF H; Interferon lambda-2-H |
| UniProt Gene Name: | IFNA14�� |
| UniProt Entry Name: | IFN14_HUMAN |
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