Cytokines Recombinant Proteins

Human IFN a 2b Recombinant Protein (RPPB0386)

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SKU:
RPPB0386
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q86UP4
Research Area:
Cytokines

Description

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Product Name:Human IFN a 2b Recombinant Protein
Product Code:RPPB0386
Size:10µg
Species:Human
Target:IFN a 2b
Synonyms:Interferon alpha 2b, IFNA, INFA2, MGC125764, MGC125765.
Source:Escherichia Coli
Physical Appearance:Colorless, clear and transparent solution.
Formulation:IFN-a 2b is supplied in solution (1.48mg/ml)�containing 20mM Acetate Buffer (pH 6.0), 0.8%NaCl and 0.005% Polysorbate 80.
Stability:IFN alpha-2b PEG should be stored refrigerated at 2� to 8°C. Vials should be kept in their�packaging to protect from light until the time of use. Shaking and freezing should be avoided.
Purity:Greater than 97.0% as determined by SEC-HPLC.
Biological Activity:The specific activity as determined in a viral resistance assay using VSV-WISH cells was found to be 3,000,000 IU/mg.
UniProt Code:Q86UP4

IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.

Interferon-a 2b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19269 Dalton. The Pegylated�IFN-a 2b is produced by attaching a 20kDa mPEG-aldehyde to the N-terminal IFN alpha-2b. Interferon-a 2b is purified by proprietary chromatographic techniques.

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