Cytokines Recombinant Proteins

Human IFN a 2b Recombinant Protein (RPPB0385)

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SKU:
RPPB0385
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q86UP4
Research Area:
Cytokines

Description

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Product Name:Human IFN a 2b Recombinant Protein
Product Code:RPPB0385
Size:50µg
Species:Human
Target:IFN a 2b
Synonyms:Interferon alpha 2b, IFNA, INFA2, IFN-? 2b, MGC125764, MGC125765.
Source:Saccharomyces cerevisiae
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:Lyophilized from a 0.2?m filtered concentrated (1mg/ml) solution in PBS, pH-7.4.
Solubility:It is recommended to reconstitute the lyophilized glycosilated IFN alpha 2b in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions.
Stability:Lyophilized glycosilated IFN-a 2b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 2b should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity:Greater than 98.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Amino Acid Sequence:The sequence of the first five N-terminal amino acids was determined and was found to be Cys-Asp-Leu-Pro-Gln
Biological Activity:The specific activity as determined in a viral resistance assay was found to be no less than 300,000,000IU/mg.
UniProt Code:Q86UP4

IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.

Interferon-alpha 2b Human Recombinant produced in yeast is a single, glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of approximately 19 kDa.The Interferon-alpha 2b gene was obtained from human leukocytes.The IFN-a 2b is purified by proprietary chromatographic techniques.

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