Cytokines Recombinant Proteins
Human IFN a 1b Recombinant Protein (RPPB0381)
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- SKU:
- RPPB0381
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8WZ68
- Research Area:
- Cytokines
Description
| Product Name: | Human IFN a 1b Recombinant Protein |
| Product Code: | RPPB0381 |
| Size: | 100µg |
| Species: | Human |
| Target: | IFN a 1b |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Lyophilized from a 0.2�m filtered solution (50ug/ml) in PBS, pH 7.4, containing 4% mannitol and 1% HSA. |
| Solubility: | It is recommended to reconstitute the lyophilized IFN alpha 1b in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Interferon alpha 1b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 1b should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 96.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | The sequence of the first five N-terminal amino acids was determined and was found to be Cys-Asp-Leu-Pro-Glu |
| Biological Activity: | The specific activity as determined in a viral resistance assay using bovine kidney MDBK cells was found to be 1 x 108 IU/ mg. |
| UniProt Code: | Q8WZ68 |
IFN-alpha 1b is produced by macrophages, IFN-alpha 1b has antiviral activities and stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
Interferon-alpha 1b Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 166 amino acids and having a molecular mass of 19392 Dalton.The Interferon-alpha 1b gene was obtained from human leukocytes.The IFN-a 1b is purified by proprietary chromatographic techniques.
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