Metabolism Recombinant Proteins

Human IDH1 Recombinant Protein (RPES2687)

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RPES2687

Description

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Human IDH1 Recombinant Protein

Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the ?-hydroxylation of phytanic acid.

Product Name:Human IDH1 Recombinant Protein (RPES2687)
Product Code:RPES2687
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Isocitrate Dehydrogenase [NADP] Cytoplasmic, IDH, Cytosolic NADP-Isocitrate Dehydrogenase, IDP, NADP(+)-Specific ICDH, Oxalosuccinate Decarboxylase, IDH1, PICD
Accession:O75874
Sequence:Met 1-Leu414
Fusion tag:C-8His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Isocitrate Dehydrogenase [NADP] Cytoplasmic is produced by our E.coli expression system and the target gene encoding Met1-Leu414 is expressed with a 8His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:48.1 kDa
AP Mol Mass:39-54 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 50mM Tris; 200mM NaCl; 10% glycerol; pH8.0.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism
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